Anatomia Patologica e Biobanche
Cross-cutting discipline for cancer research activities
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Secretary
Caterina Marchiò
IRCCS CANDIOLO
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Clinical Coordinator
Massimo Barberis
IEO MILANO
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Pre-clinical Coordinator
Angelo Paradiso
IRCS GIOVANNI P.II - BARI
The pre-analytic procedures implemented in the laboratories of Pathological Anatomy have a substantial impact on genomic analyses, from their feasibility to the correct interpretation of the results.
From here rises the need to actively involve the Anatomic Pathology of IRCCS that adheres to ACC in the network design strategies and make more homogeneous flows of collection/analysis of samples that will constitute the valuable substrate of the analysis provided by the different pathology-specific WG. Currently, the AP of 23 IRCCS adhere, and AIMaC (Italian Association of Cancer Patients) has also expressed interest in this WG.
The primary objective of the Pathology and Biobanking WG – coordinated by Caterina Marchiò of IRCCS Candiolo – is therefore to organize a common path to standardize the quality of biological samples, primarily tissue specimens, which are sent for diagnostic purposes to Pathological Anatomy, but which could be necessary for clinical trials, validation studies of molecular investigations or for the establishment of a certified biobank. Given the central role of the quality of nucleic acids (DNA and RNA) extracted from tissues for downstream molecular analysis, a Pathologist referent and a Biologist referent (molecular) have been involved for each Pathology Anatomy.
To achieve the expected results, we will proceed first with the acquisition of the individual document institutes of the International Organization for Standardization (ISO) for the pre-analytic phase preceding the extraction of nucleus acids from paraffin and frozen tissue. It will follow the elaboration of the standard operating procedures (SOP) typical for the pre-analytic phase to be shared between the Pathological Anatomies adherents. Project effectiveness will be assessed in a project that aims to implement the same formalin setting conditions in a systematic way within the Gersom project. These steps will be the fundamental substrate of the WG to provide a standard preliminary address for bio-banking activities.
Il Team
- Pre Clinici
- Clinici
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HUMANITAS
Salvatore Lorenzo Renne
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IDI ROMA
Stefania D’Atri
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INT IRCCS MILANO
Laura Cattaneo
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IRST MELDOLA
Valentina Ancarani
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ONCOLOGICO BARI
Alfredo Francesco Zito
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ONCOLOGICO BARI
Raffaella Massafra
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ONCOLOGICO BARI
Giuseppe De Palma
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OPBG ROMA
Tiziana Franchin
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CSS S.G. ROTONDO
Paolo Graziano
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IRE ROMA
Simona Di Martino
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IRCCS DE BELLIS
Pasqua Letizia Pesole
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AUSL IRCCS
Eleonora Zanetti
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IEO MILANO
Elena Guerini-Rocco
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IRCCS GEMELLI ROMA
Guido Rindi
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IRCCS CROB
Daniela Lamorte
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IRCCS CROB
Luciana Possidente
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IRCCS CANDIOLO
Giuliana Cavalloni
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INT PASCALE
Giosuè Scognamiglio, Francesca Collina
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IST GENOVA
Monica Marchese
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ICS MAUGERI
Marta Truffi
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SAN MATTEO
Roberta Riboni
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IRCCS AOU BOLOGNA
Donatella Santini
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IRCCS IOR
Enrico Lucarelli
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IRCCS GENOVA
Monica Marchese
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IRCCS AOU BOLOGNA
Dario De Biase
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IRCCS S. CUORE DON CALABRIA
Chiara Pighi
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ONCOLOGICO BARI
Margherita Patruno
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AUSL IRCCS
Simonetta Piana
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CRO AVIANO
Vincenzo Canzonieri
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HUMANITAS
Annarita Destro
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IOV PADOVA
Antonio Scapinello
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BESTA MILANO
Bianca Pollo
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IRCCS SAN RAFFAELE MI
Maurilio Ponzoni
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CSS S.G. ROTONDO
Paolo Graziano
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IRCCS CANDIOLO
Gianluca Vitel
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IRCCS GEMELLI ROMA
Guido Rindi
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IRCCS IRE
Giovanni Cigliana
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IRCCS DE BELLIS
Raffaele Armentano
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INT PASCALE
Maurizio Di Bonito
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IDI ROMA
Francesca Ricci
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IRCCS CROB
Giuseppe Patitucci
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INT MILANO
Andrea Vingiani
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OPBG ROMA
Rita Alaggio
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IRCCS GENOVA
Luca Mastracci
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ICS MAUGERI
Laura Villani
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IEO MILANO
Massimo Barberis
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SAN MATTEO
Marco Paulli
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IRCCS IOR BOLOGNA
Alberto Righi
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IRCCS SDN
Giovanni Smaldone
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IRCCS AOU BOLOGNA
Giovanni Tallini
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IRCCS AOU BOLOGNA
Marco Seri
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IRCCS S. CUORE DON CALABRIA
Anna Pesci
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IRCCS S. CUORE DON CALABRIA
Alessandro Inno